When using gas or liquid chromatography for pesticide residue analysis, the matrix effect will seriously affect the accurate quantification and qualitative determination of certain analytes. The matrix effect is investigated and evaluated and effective measures are taken to eliminate or compensate. An indispensable part of the method development and verification process. This article reviews the causes and influencing factors of matrix effects in the analysis of pesticide residues in food, and discusses effective measures to overcome matrix effects. Therefore, this article has great reference value.

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